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Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors in the central nervous system, conolidine modulates alternate molecular targets. A Science Innovations analyze identified that conolidine interacts With all the atypical chemokine receptor ACKR3/CXCR7, w
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" To this point, the compound has shown remarkably couple of, if any, Unwanted side effects, but that is something of the double-edged sword. "The dearth of Unwanted effects causes it to be a very good prospect for improvement," Bohn stated. "Then again, if there were Negative effects, they might provide extra clues regarding how the compound perfo